Franck Morel Selected Research

Oncostatin M

1/2019	Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFβ1 on fibrosis markers.
11/2018	Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression.
1/2016	Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation.
3/2013	Involvement of IL-1 and oncostatin M in acanthosis associated with hypertensive leg ulcer.
1/2010	Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1{alpha}, and TNF-{alpha} Recapitulates Some Features of Psoriasis.
4/2007	Oncostatin M secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation.

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Franck Morel Research Topics

Disease

14	Inflammation (Inflammations) 01/2020 - 04/2007
8	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2017 - 12/2005
4	Neoplasms (Cancer) 09/2021 - 01/2015
3	Hyperplasia 11/2018 - 03/2005
2	Exanthema (Rash) 11/2020 - 01/2020
2	Dermatitis 01/2020 - 01/2016
2	Infections 06/2018 - 07/2014
2	Burns 03/2016 - 09/2014
2	Atopic Dermatitis (Atopic Eczema) 01/2012 - 04/2007
1	Breast Neoplasms (Breast Cancer) 09/2021
1	Colorectal Neoplasms (Colorectal Cancer) 11/2020
1	Vitiligo 01/2020
1	Schnitzler Syndrome 01/2020
1	Fever (Fevers) 01/2020
1	Fibrosis (Cirrhosis) 01/2019
1	Cicatrix (Scar) 01/2019
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2018
1	Erythema 01/2016
1	Fatty Liver 01/2016
1	Skin Diseases (Skin Disease) 10/2015
1	Carcinogenesis 01/2015
1	Wounds and Injuries (Trauma) 09/2014
1	Ulcer 03/2013
1	Leg Ulcer 03/2013
1	Mevalonate Kinase Deficiency 09/2009
1	Brain Injuries (Brain Injury) 10/2007
1	Cardiomegaly (Heart Hypertrophy) 07/2003

Drug/Important Bio-Agent (IBA)

15	CytokinesIBA 11/2020 - 07/2003
6	Interleukin-17 (Interleukin 17)IBA 01/2020 - 01/2010
6	Oncostatin MIBA 01/2019 - 04/2007
6	Interleukin-22 (IL-22)IBA 01/2017 - 03/2005
5	Interleukin-6 (Interleukin 6)IBA 01/2020 - 07/2003
4	Imiquimod (Aldara)FDA LinkGeneric 01/2020 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2015
3	Interleukin-1 (Interleukin 1)IBA 10/2015 - 09/2009
3	ChemokinesIBA 07/2014 - 01/2010
3	Antimicrobial PeptidesIBA 07/2014 - 01/2010
2	Interleukin-4 (Interleukin 4)IBA 11/2020 - 01/2012
2	Interleukin-10 (Interleukin 10)IBA 01/2020 - 12/2005
2	SuspensionsIBA 03/2016 - 09/2014
1	OligosaccharidesIBA 09/2021
1	Heparitin Sulfate (Heparan Sulfate)IBA 09/2021
1	Matrix Metalloproteinases (MMPs)IBA 09/2021
1	SugarsIBA 09/2021
1	Polysaccharides (Glycans)IBA 09/2021
1	heparanaseIBA 09/2021
1	CarrageenanIBA 09/2021
1	ErbB Receptors (EGF Receptor)IBA 11/2020
1	Cetuximab (Erbitux)FDA Link 11/2020
1	Monoclonal AntibodiesIBA 11/2020
1	Interleukin-8 (Interleukin 8)IBA 11/2020
1	Interleukin-23 (Interleukin 23)IBA 11/2020
1	Cadherins (E-Cadherin)IBA 01/2020
1	Immunoglobulin M (IgM)IBA 01/2020
1	Chemokine CCL20IBA 01/2020
1	Ethanol (Ethyl Alcohol)IBA 01/2020
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2020
1	Virulence Factors (Pathogenicity Factors)IBA 06/2018
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2017
1	AntibodiesIBA 01/2016
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 10/2015
1	InflammasomesIBA 10/2015
1	interleukin-22 receptor (IL-22R)IBA 01/2015
1	Differentiation AntigensIBA 01/2014
1	Biological ProductsIBA 01/2012
1	Interleukin-13IBA 01/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2010
1	Simvastatin (Zocor)FDA LinkGeneric 09/2009
1	Mevalonic Acid (Mevalonate)IBA 09/2009
1	Terpenes (Terpenoids)IBA 09/2009

Therapy/Procedure

2	Intradermal Injections 01/2016 - 01/2016
1	Therapeutics 11/2020
1	Transplantation 09/2014
1	Cell Transplantation 10/2007